Leonardo Vando, MD

Research & Media

Peer-reviewed research, clinical commentary, and press on ketamine therapy, addiction psychiatry, and telehealth.

Peer-reviewed publications

Peer-reviewed

At-Home Telehealth-Supported Subcutaneous Ketamine Therapy for Safety, Feasibility, and Clinical Outcomes in Adults With Moderate to Severe Depression, Anxiety, or Posttraumatic Stress Disorder in a Large, Heterogeneous Cohort in the United States: Retrospective Cohort Study

Parks AC, Woodward AL, Henry RD, Arden KA, Vando L, Swain J, Lamichhane B.

Journal of Medical Internet Research

Retrospective evaluation of at-home subcutaneous ketamine in 3,870 patients across 38 states; the study reported feasibility and symptom improvements in depression, anxiety, and PTSD.

PMC · Read
Peer-reviewed

At-home, telehealth-supported ketamine treatment for depression: Findings from longitudinal, machine learning and symptom network analysis of real-world data

Mathai DS, Hull TD, Vando L, Malgaroli M.

Journal of Affective Disorders

Real-world outcomes from 11,441 patients, with machine-learning and symptom-network analyses of treatment response.

Peer-reviewed

At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: Findings from a large, prospective, open-label effectiveness trial

Hull TD, Malgaroli M, Gazzaley A, Akiki TJ, Madan A, Vando L, Arden K, Swain J, Klotz M, Paleos C.

Journal of Affective Disorders

Prospective, open-label effectiveness trial of 1,247 adults receiving at-home sublingual ketamine with telehealth support; the study reported improvements in anxiety and depression and described adverse events.

Preprints

Preprint — not yet peer-reviewed

At-Home Ketamine-Assisted Therapy for Post-Traumatic Stress Disorder: A Real-World Retrospective Analysis

Swain J, Carter D, Vando L.

Research Square

Retrospective analysis of 374 adults with moderate-to-severe PTSD who completed a six-session at-home ketamine-assisted therapy program.

Presentations

Presentation

American Psychiatric Association Annual Meeting — San Francisco

Presented real-world outcomes of at-home, telehealth-supported ketamine treatment: improvement in most patients after four sessions, resolution of suicidal ideation in a majority of those who reported it at baseline, and results comparable to in-clinic IV ketamine. Video interview: Healio Psychiatry, June 27, 2023.

Psych Pulse

Weekly column by Dr. Vando translating new psychiatric and addiction trials into clinical and trial-design implications.

Read the column

Press & media

Featured

Healio Psychiatry

Video: At-home ketamine treatment comparable to IV in-clinic

Video interview from the APA Annual Meeting on at-home ketamine outcomes versus in-clinic IV treatment.

Behavioral Health Business

Quoted in coverage of public comments opposing the DEA's proposed telehealth controlled-substance rules, arguing access should be based on medical need, not geography or wealth.

Healthline

Quoted as study author on the first large at-home sublingual ketamine study and the role of clinician screening.

Behavioral Health Business

Interviewed on growth of therapeutic ketamine providers and the safeguards safe ketamine care requires.

Forbes

Explained ketamine's mechanism, neuroplasticity, and the importance of preparation and integration.

High Times

Ketamine Discoveries Continue to Come as Further Clarity is Needed

Coverage of ketamine research and regulatory context, identifying Dr. Vando as Mindbloom’s medical director and including his clinical commentary.

More coverage

Mindbloom Evidence

Announcement of the first peer-reviewed outcomes for at-home subcutaneous ketamine.

Nutrition Insight

Coverage of a PTSD-focused ketamine therapy program; Dr. Vando cited as medical director and study co-author.

Synapse (Patsnap)

Industry coverage of the 11,441-patient study, quoting Dr. Vando as co-author.

Mindbloom

Largest Study of Psychedelic Medicine, With 11,441 Mindbloom Clients, Demonstrates Effectiveness and Safety of Guided At-home Ketamine Therapy

Mindbloom announcement of the 2024 Journal of Affective Disorders study, quoting co-author Dr. Vando. Dr. Vando serves as Mindbloom’s Medical Director.

PR Newswire

Announcement of the 11,441-patient study; Dr. Vando quoted as co-author on at-home ketamine as an effective, fast-acting option.

The Purist

Explained how ketamine quiets the default mode network, which contraindications rule patients out, and why integration matters.

Psychedelic Health (UK)

Quoted on the launch of expert-led ketamine therapy programs for heartbreak, burnout, and other life challenges.

Mindbloom

Mindbloom Comment on DEA Proposed Telemedicine Regulation

Public comment authored by Dr. Vando, as Mindbloom Medical Director, on the DEA’s proposed telemedicine prescribing rule.

Mindbloom

Results of landmark Mindbloom study exceed those of traditional antidepressant studies

Mindbloom summary of the 2022 Journal of Affective Disorders study, with commentary from Dr. Vando as Medical Director.

The New York Times

Article on ketamine therapy and depression. Included as related reading; a mention of Dr. Vando has not been verified.

Mindbloom

How Guided Psychedelic Therapy Works

Mindbloom article in which Dr. Vando discusses the role of clinical guidance during ketamine treatment.

Mindbloom Research & Clinical Content

Medical reviewer of Mindbloom's patient-education library (ketamine safety, ketamine as a psychedelic, the therapeutic process, continuing treatment) and featured researcher on the evidence hub.

Qwoted expert source profile

Expert source profile.

Murad Well Connected

Are psychedelics the future of mental wellness?

Quoted on the future of psychedelic medicine, predicting ketamine will become a leading treatment for depression and anxiety.

YouTube · Trey Tucker (Rugged Counseling)

Why Everyone's Talking About Ketamine - Psychiatrist Dr. Leo Vando of Mindbloom

Video conversation with Dr. Vando about ketamine therapy and why it has drawn growing clinical attention.

Roles & professional service

  • Medical Director, Mindbloom (national at-home ketamine therapy platform)
  • Founder & Principal Investigator, Dr. Vando Medical Services, PC / Vando Telehealth
  • Weekly columnist, “Psych Pulse,” Clinical Trial Vanguard
  • Editorial review board, NSCA Personal Training Quarterly
  • Investigator, industry-sponsored clinical trials in major depressive disorder and tardive dyskinesia (phase 3–4)
  • Participant, NYS OASAS Opioid Treatment Program Medical Director Collaborative
  • Training: MD, Ponce School of Medicine (2001); Psychiatry residency (2001–2005) and Addiction Psychiatry fellowship (2005–2006), Beth Israel Medical Center / Icahn School of Medicine at Mount Sinai; BS Chemistry, Sacred Heart University
  • Double board-certified: Psychiatry & Addiction Psychiatry (ABPN)

Patient experience

4.8 out of 5 from 300+ verified patient reviews on Zocdoc

See reviews on Zocdoc

Last updated: October 2026